How does Cerazette work?

Primary mode of action: inhibits ovulation

  • Cerazette is the first and only estrogen-free pill to primarily inhibit ovulation.1,2,8,9
  • Ovulation is inhibited for up to 36 hours, giving Cerazette a 'missed pill' window of 12 hours that is comparable to combined oral contraceptives (COCs).1,6,7
  • In contrast, traditional progestogen-only pills (POPs) do not consistently inhibit ovulation and are only effective for up to 27 hours, giving them a 3-hour 'missed pill' window.8,9
  • There is also less risk of ectopic pregnancy with Cerazette than with traditional POPs which primarily work by thickening the cervical mucus.1,8,9
  • Cerazette therefore offers similar reliability and convenience as COCs but greater flexibility of dosing than traditional POPs.1,6–9

Secondary mode of action: thickens cervical mucus

  • Cerazette increases the viscosity of the cervical mucus, making it less penetrable by sperm.1

Summary of Cerazette's contraceptive effects

Summary of Cerazette's contraceptive effects

† Traditional POPs offer no consistent inhibitory effect on ovulation

 

 

Adverse events should be reported. Reporting forms and information can be found at www.yellowcard.gov.uk.
Adverse events should also be reported to MSD Drug Safety Department on 01707 363773

Organon

Date of Preparation 9/09
Job Code 9/12 - CZT.10.GB.42040.AV

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